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Recently, synthetic cannabinoids originally designed for testing in the laboratory only have found use recreationally in designer herbal blends “Spice”.

Drug discrimination of these compounds offers a specific behavioral test that can help determine whether these new synthetic compounds.

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By utilization of drug discrimination and other behavioral techniques, a better understanding of these new “designer” cannabinoids may be reached to assist in treating both the acute and chronic effects of these drugs.

Finally the paper provides a brief exposé of modern cannabinoid research as a backdrop to the recreational use of designer herbal blend cannabimimetics.

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